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Retatrutide produced 24.2% average weight loss at the 12mg dose over 48 weeks in Phase 2 trials

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The SELECT trial's cardiovascular benefit data (20% MACE reduction) has been particularly influential in changing payer attitudes, because preventing heart attacks and strokes saves money long-term

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Conflict of interest The author(s) declared that this work was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest

The glucagon receptor activation is where Retatrutide separates itself from the field entirely